2018

Proteasomal Protein Degradation: Adaptation of Cellular Proteolysis With Impact on Virus—and Cytokine-Mediated Damage of Heart Tissue During Myocarditis
Frontiers in Immunology
Antje Beling und Meike Kespohl

DOI: 10.3389/fimmu.2018.02620

Mit Beteiligung des Projektes: TP02

---

Silencing the CSF-1 Axis Using Nanoparticle Encapsulated siRNA Mitigates Viral and Autoimmune
Myocarditis
Frontiers in Immunology
Ingmar Sören Meyer, Carl Christoph Goetzke, Meike Kespohl, Martina Sauter, Arnd Heuser, Volker Eckstein, Hans-Peter Vornlocher, Daniel G. Anderson, Jan Haas, Benjamin Meder, Hugo Albert Katus, Karin Klingel, Antje Beling und Florian Leuschner

DOI: 10.3389/fimmu.2018.02303

Mit Beteiligung des Projektes: TP02

---

Tumor immunoevasion via acidosis-dependent induction of regulatory tumor-associated macrophages
Nature Immunology
Toszka Bohn, Steffen Rapp, Natascha Luther, Matthias Klein, Till-Julius Bruehl, Nobuhiko Kojima, Pamela Aranda Lopez, Jennifer Hahlbrock, Sabine Muth, Shogo Endo, Stefanie Pektor, Almut Brand, Kathrin Renner, Vanessa Popp, Katharina Gerlach, Dennis Vogel, Christina Lueckel, Danielle Arnold-Schild, Jacques Pouyssegur, Marina Kreutz, Magdalena Huber, Jochem Koenig, Benno Weigmann, Hans-Christian Probst, Esther von Stebut, Christian Becker, Hansjoerg Schild, Edgar Schmitt, Tobias Bopp

Mit Beteiligung der Projekte: TP1, TP13, TP15

---

Fungi enter the stage of colon carcinogenesis
Immunity
Claire Conche, Florian R Greten

DOI: 10.1016/j.immuni.2018.09.002.

Mit Beteiligung des Projektes: TP16

---

Mitophagy in intestinal epithelial cells triggers adaptive immunity during tumorigenesis
Cell
Paul K Ziegler, Julia Bollrath, Charles K Pallangyo, Takaji Matsutani, Özge Canli, Tiago De Oliveira, Michaela A Diamanti, Nina Müller, Jaba Gamrekelashvili, Tracy Putoczki, David Horst, Arun K Mankan, Meryem G Öner, Susanna Müller, Josef Müller-Höcker, Thomas Kirchner, Julia Slotta-Huspenina, M. Mark Taketo, Thomas Reinheckel, Stefan Dröse, Andrew C Larner, Winfried S Wels, Matthias Ernst, Tim F Greten, Melek C Arkan, Thomas Korn, Dagmar Wirth, Florian R Greten

DOI: 10.1016/j.cell.2018.05.028

Mit Beteiligung des Projektes: TP16

---

USP18 (UBP43) abrogates p21-mediated inhibition of HIV-1
Journal of Virology
Edmund Osei Kuffour, Kerstin Schott, Ananda Ayyappan Jaguva Vasudevan, Jessica Holler, Wolfgang A. Schulz, Philipp A. Lang, Karl S. Lang, Baek Kim, Dieter Häussinger, Renate König, Carsten Münk

DOI: 10.1128/JVI.00592-18.

Mit Beteiligung des Projektes: TP04

---

The Myb-related protein MYPOP is a novel intrinsic host restriction factor of oncogenic human papillomaviruses
Oncogene
Elena Wüstenhagen, Fatima Boukhallouk, Inka Negwer, Krishnaraj Rajalingam, Frank Stubenrauch, Luise Florin

DOI: 10.1038/s41388-018-0398-6

Mit Beteiligung des Projektes: TP05

---

Mouse model of cytomegalovirus disease and immunotherapy in the immunocompromised host: predictions for medical translation that survived the "Test of Time"
Viruses
Matthias J Reddehase, Niels A Lemmermann

DOI: 10.3390/v10120693.

Mit Beteiligung des Projektes: TP11

---

Targeting prohibitins at the cell surface prevents Th17-mediated autoimmunity
EMBO Journal
Ulrike Buehler, Katharina Schulenburg, Hajime Yurugi, Maja Šolman, Daniel Abankwa, Alexander Ulges, Stefan Tenzer, Tobias Bopp, Bernd Thiede, Frauke Zipp, Krishnaraj Rajalingam

DOI: 10.15252/embj.201899429

Mit Beteiligung der Projekte: TP05, TP09, TP01, Z01

---

EGFL7 enhances surface expression of integrin α5β1to promote angiogenesis in malignant brain tumors
EMBO Molecular Medicine
Nevenka Dudvarski Stanković, Frank Bicker, Stefanie Keller, David TW Jones, Patrick N Harter, Arne Kienzle, Clarissa Gillmann, Philipp Arnold, Anna Golebiewska, Olivier Keunen, Alf Giese, Andreas von Deimling, Tobias Bäuerle, Simone P Niclou, Michel Mittelbronn, Weilan Ye, Stefan M Pfister, Mirko HH Schmidt

DOI 10.15252/emmm.201708420

Mit Beteiligung des Projektes: TP09

---

Dephosphorylation of the HIV-1 restriction factor SAMHD1 is mediated by PP2A-B55α holoenzymes during mitotic exit
Nature Communications
Kerstin Schott, Nina V. Fuchs, Rita Derua, Bijan Mahboubi, Esther Schnellbächer, Janna Seifried, Christiane Tondera, Heike Schmitz, Caitlin Shepard, Alberto Brandariz-Nuñez, Felipe Diaz-Griffero, Andreas Reuter, Baek Kim, Veerle Janssens & Renate König

DOI:10.1038/s41467-018-04671-1

Mit Beteiligung des Projektes: TP04

---