2024

Rapid protection against viral infections by chemokine-accelerated post-exposure vaccination

Front Immunol

Heine A, Lemmermann NAW, Flores C, Becker-Gotot J, Garbi N, Brossart P, Kurts C

10.3389/fimmu.2024.1338499

TP11

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Modulation of cytomegalovirus immune evasion identifies direct antigen presentation as the predominant mode of CD8 T-cell priming during immune reconstitution after hematopoietic cell transplantation

Front Immunol

Holtappels R, Büttner JK, Freitag K, Reddehase MJ, Lemmermann NA

10.3389/fimmu.2024.1355153

TP11

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Reciprocal crosstalk between Th17 and mesothelial cells promotes metastasis-associated adhesion of ovarian cancer cells

Clin Transl Med 

Neuhaus F, Lieber S, Shinkevich V, Steitz AM, Raifer H, Roth K, Finkernagel F, Worzfeld T, Burchert A, Keber C, Nist A, Stiewe T, Reinartz S, Beutgen VM, Graumann J, Pauck K, Garn H, Gaida M, Müller R, Huber M

10.1002/ctm2.1604

TP22, TPQ1

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Cytokine-responsive T- and NK-cells portray SARS-CoV-2 vaccine-responders and infection in multiple myeloma patients

Leukemia

Enssle JC, Campe J, Moter A, Voit I, Gessner A, Yu W, Wolf S, Steffen B, Serve H, Bremm M, Huenecke S, Lohoff M, Vehreschild M, Rabenau HF, Widera M, Ciesek S, Oellerich T, Imkeller K, Rieger MA, von Metzler I, Ullrich E

10.1038/s41375-023-02070-0

TP5, TP12

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Nucleic acid sensing promotes inflammatory monocyte migration through biased coagulation factor VIIa signaling

Blood

Zelaya H, Grunz K, Nguyen TS, Habibi A, Witzler C, Reyda S, Gonzalez-Menendez I, Quintanilla-Martinez L, Bosmann M, Weiler H, Ruf W

10.1182/blood.2023021149

TP02, TP10

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Targeting the tissue factor coagulation initiation complex prevents antiphospholipid antibody development

Blood

Müller-Calleja N, Grunz K, Nguyen TS, Posma J, Pedrosa D, Meineck M, Hollerbach A, Braun J, Muth S, Schild H, Saar K, Hübner N, Krishnaswamy S, Royce J, Teyton L, Lemmermann N, Weinmann-Menke J, Lackner KJ, Ruf W

10.1182/blood.2023022276

TP02, TP11, TP13, TP21N

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Immune damage in Long Covid

Science

Ruf W

10.1126/science.adn1077

TP02

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TF-FVIIa PAR2-β-Arrestin Signaling Sustains Organ Dysfunction in Coxsackievirus B3 Infection of Mice

Arterioscler Thromb Vasc Biol

Kespohl M, Goetzke CC, Althof N, Bredow C, Kelm N, Pinkert S, Bukur T, Bukur V, Grunz K, Kaur D, Heuser A, Mülleder M, Sauter M, Klingel K, Weiler H, Berndt N, Gaida MM, Ruf W, Beling A

10.1161/ATVBAHA.123.320157

TP02, TP22N

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ISG15 blocks cardiac glycolysis and ensures sufficient mitochondrial energy production during Coxsackievirus B3 infection

Cardiovasc Res

Bredow C, Thery F, Wirth EK, Ochs S, Kespohl M, Kleinau G, Kelm N, Gimber N, Schmoranzer J, Voss M, Klingel K, Spranger J, Renko K, Ralser M, Mülleder M, Heuser A, Knobeloch KP, Scheerer P, Kirwan J, Brüning U, Berndt N, Impens F, Beling A

10.1093/cvr/cvae026

TP02